Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26423451 | 1.00 | KDM4E (0.36) | KDM4EALDH1A1CYP3A4PIK3CALMNA | |
| SCHEMBL26423369 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1CYP3A4PIK3CALMNA | |
| SCHEMBL26423480 | 0.79 | MAPK14 (0.39) | KDM4EALDH1A1CYP3A4LMNANPC1 | |
| SCHEMBL26423468 | 0.79 | MAPK14 (0.39) | KDM4EALDH1A1CYP3A4LMNANPC1 | |
| SCHEMBL26423471 | 0.78 | DAGLA (0.32) | KDM4EALDH1A1LATS1LATS2F7 | |
| SCHEMBL26423473 | 0.78 | DAGLA (0.32) | KDM4EALDH1A1LATS1LATS2F7 | |
| SCHEMBL26423461 | 0.76 | IDO1 (0.34) | KDM4EALDH1A1LATS1LATS2F7 | |
| SCHEMBL26423460 | 0.76 | IDO1 (0.34) | KDM4EALDH1A1LATS1LATS2F7 | |
| SCHEMBL26423457 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1CYP3A4PIK3CALMNA | |
| SCHEMBL26423449 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1CYP3A4PIK3CALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127291-A1 | HETEROCYCLIC ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY PANEL | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127291-A1 | HETEROCYCLIC ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY PANEL | OCIAD2, OCIAD1, AZI2 | KDM4E 2800/4885ALDH1A1 302/4885CYP3A4 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.