Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30419362 | 1.00 | PARP1 (0.40) | PARP1TSHRSETD7HSD11B1MAP4K4 | |
| SCHEMBL31084572 | 1.00 | PARP1 (0.40) | PARP1TSHRSETD7HSD11B1MAP4K4 | |
| SCHEMBL26427727 | 1.00 | PARP1 (0.40) | PARP1TSHRSETD7HSD11B1MAP4K4 | |
| SCHEMBL30867754 | 0.83 | SETD7 (0.39) | TSHRSETD7MAP4K4CHRM2CHRM1 | |
| SCHEMBL102293 | 0.81 | PARP1 (0.46) | PARP1SETD7MAP4K4CHRM2CHRM1 | |
| SCHEMBL103217 | 0.81 | PARP1 (0.46) | PARP1SETD7MAP4K4CHRM2CHRM1 | |
| SCHEMBL102292 | 0.81 | PARP1 (0.46) | PARP1SETD7MAP4K4CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL377440 | 0.80 | PARP1 (0.45) | PARP1SETD7MAP4K4CHRM2CHRM1 | |
| Potassium SCHEMBL30616188 | 0.80 | PARP1 (0.45) | PARP1SETD7MAP4K4CHRM2CHRM1 | |
| Methane SCHEMBL28975622 | 0.80 | PARP1 (0.45) | PARP1SETD7MAP4K4CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067353-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |