Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.47 |
| ▸ | MLNR | O43193 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26427998 | 1.00 | FUCA1 (0.47) | FUCA1MLNRCYP3A4S1PR5S1PR1 | |
| SCHEMBL22530421 | 1.00 | FUCA1 (0.47) | FUCA1MLNRCYP3A4S1PR5S1PR1 | |
| SCHEMBL26428016 | 1.00 | FUCA1 (0.47) | FUCA1MLNRCYP3A4S1PR5S1PR1 | |
| SCHEMBL30419036 | 0.86 | S1PR5 (0.52) | FUCA1MLNRCYP3A4S1PR5S1PR1 | |
| SCHEMBL23464746 | 0.81 | MEN1 (0.46) | FUCA1S1PR5S1PR1MEN1KMT2A | |
| SCHEMBL2706345 | 0.81 | MEN1 (0.46) | FUCA1S1PR5S1PR1MEN1KMT2A | |
| SCHEMBL203039 | 0.81 | MEN1 (0.46) | FUCA1S1PR5S1PR1MEN1KMT2A | |
| SCHEMBL3522693 | 0.80 | FUCA1 (0.55) | FUCA1MLNRCYP3A4S1PR5S1PR1 | |
| SCHEMBL4279682 | 0.80 | FUCA1 (0.55) | FUCA1MLNRCYP3A4S1PR5S1PR1 | |
| SCHEMBL3522692 | 0.80 | FUCA1 (0.55) | FUCA1MLNRCYP3A4S1PR5S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067353-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |