⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581302 | 0.78 | — | — | |
| SCHEMBL2697704 | 0.78 | — | — | |
| SCHEMBL25811722 | 0.74 | — | — | |
| SCHEMBL30129816 | 0.74 | — | — | |
| SCHEMBL2037302 | 0.73 | EPHX2 (0.43) | — | |
| SCHEMBL255507 | 0.72 | — | — | |
| SCHEMBL15624391 | 0.72 | TDP1 (0.44) | — | |
| SCHEMBL29457380 | 0.72 | — | — | |
| SCHEMBL13261586 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL34460386 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028441-A | A kind of fluoro- 2-(1- bromine cyclopropyl of 5-) pyridine synthetic method | 江苏工程职业技术学院 | 2019-07-19 | — | — | CN | claimed |
| EP-4648763-A2 | COMPOUNDS FOR FGFRS INHIBITORS | Cogent Biosciences, Inc. (US) | 2025-11-19 | — | — | EP | disclosed |
| CN-120202198-A | Thioether compound with soft drug property, pharmaceutical composition and application thereof | 北京普祺医药科技股份有限公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-113490668-B | Compounds and compositions for the treatment of diseases associated with APJ receptor activity | 安娜普尔纳生物股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| US-20240270741-A1 | COMPOUNDS FOR FGFRS INHIBITORS | COGENT BIOSCIENCES, INC. | 2024-08-15 | — | — | US | disclosed |
| WO-2024151638-A2 | COMPOUNDS FOR FGFRS INHIBITORS | COGENT BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024151638-A2 | COMPOUNDS FOR FGFRS INHIBITORS | COGENT BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| US-20230365592-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. | 2023-11-16 | — | — | US | disclosed |
| US-20230227466-A1 | SUBSTITUTED THIENOPYRIMIDINES THAT INTERACT WITH THE RAS SUPERFAMILY FOR THE TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | SHY THERAPEUTICS, LLC | 2023-07-20 | — | — | US | disclosed |
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |
| EP-3497093-A1 | SULFONYL PYRIDYL TRP INHIBITORS | H. Hoffnabb-La Roche Ag (CH) | 2019-06-19 | — | — | EP | disclosed |
| US-20190167681-A1 | SULFONYL PYRIDYL TRP INHIBITORS | GENENTECH, INC. (US) | 2019-06-06 | — | — | US | disclosed |
| US-20190167681-A1 | SULFONYL PYRIDYL TRP INHIBITORS | GENENTECH, INC. (US) | 2019-06-06 | — | — | US | disclosed |
| WO-2018029288-A1 | SULFONYL PYRIDYL TRP INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-02-15 | — | — | WO | disclosed |
| WO-2018029288-A1 | SULFONYL PYRIDYL TRP INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-02-15 | — | — | WO | disclosed |
| CN-103755754-A | N-acetyl-3,4,6-triacetyl-beta-D-glucosaminidase compound and hydrolyzate thereof and preparation methods of compound and hydrolyzate | UNIV NINGBO | 2014-04-30 | — | — | CN | disclosed |
| CN-103755755-A | N-acetyl-3,4,6-triacetyl-beta-D-glucosaminidase compound and hydrolyzate thereof and preparation methods of compound and hydrolyzate | UNIV NINGBO | 2014-04-30 | — | — | CN | disclosed |
| US-7687502-B2 | Substituted quinazoline or pyridopyrimidine derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| US-20080032996-A1 | Substituted Quinazoline or Pyridopyrimidine Derivative | MSD K.K. (JP) | 2008-02-07 | — | — | US | disclosed |
| EP-1734040-A1 | SUBSTITUTED QUINAZOLINE OR PYRIDOPYRIMIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-12-20 | — | — | EP | disclosed |