⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28830774 | 0.81 | TSHR (0.35) | — | |
| SCHEMBL2308529 | 0.80 | — | — | |
| SCHEMBL1180013 | 0.79 | ELANE (0.36) | — | |
| SCHEMBL9149533 | 0.78 | — | — | |
| SCHEMBL9688370 | 0.77 | — | — | |
| SCHEMBL120221 | 0.77 | — | — | |
| SCHEMBL8678717 | 0.74 | ELANE (0.33) | — | |
| SCHEMBL11858398 | 0.74 | ELANE (0.33) | — | |
| SCHEMBL9687080 | 0.74 | — | — | |
| SCHEMBL37236 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238213-A1 | SOLID-PHASE SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING N6-(2-DEOXY-ALPHA,BETA-DERYTHROPENTOFURANOSYL)-2,6-DIAMINO-4-HYDROXY-5-FORMAMIDOPYRIMIDINE (Fapy.dG) | THE JOHNS HOPKINS UNIVERSITY | 2021-08-05 | — | — | US | claimed |
| US-9902693-B2 | Preparation method for pyrrolidine-2-carboxylic acid derivatives | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2018-02-27 | — | — | US | claimed |
| US-20160145208-A1 | Preparation method for pyrrolidine-2-carboxylic acid derivatives | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2016-05-26 | — | — | US | claimed |
| EP-3015456-A1 | PREPARATION METHOD FOR PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2016-05-04 | — | — | EP | claimed |
| CN-103339116-A | Substituted n-valeramide compound, preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2013-10-02 | — | — | CN | claimed |
| EP-0649424-A1 | DIOXCYCLOBUTENE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | Knoll AG (DE) | 1995-04-26 | — | — | EP | claimed |
| CN-118647605-A | Mesoionic arylpyridazinium derivatives or salts thereof, pesticides containing the same and methods of use thereof | 日本农药株式会社 | 2024-09-13 | — | — | CN | disclosed |
| CN-117777345-A | Low-melting-point polyvinyl alcohol resin with medium-temperature water solubility and preparation method thereof | 明新旭腾新材料股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11912734-B2 | Solid-phase synthesis of oligonucleotides containing N6-(2-deoxy-alpha,beta-derythropentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine (Fapy⋅dG) | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-02-27 | — | — | US | disclosed |
| CN-111406233-B | Photosensitive resin composition, dry film resist and cured product thereof | 日本化药株式会社 | 2023-12-26 | — | — | CN | disclosed |
| WO-2023141636-A1 | PRODRUGS OF 2-BROMO-LSD (2-BROMOLYSERGIC ACID DIETHYLAMIDE) | TERRAN BIOSCIENCES INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| CN-115785142-B | Carbazole aryne precursor compound and preparation method and application thereof | 成都摩诃大龙医药科技有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-115785142-A | Carbazole aryne precursor compound and preparation method and application thereof | 成都摩诃大龙医药科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| EP-0124476-B1 | CARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1988-06-22 | — | — | EP | disclosed |
| EP-0264901-A1 | Acylation products of bis(2-imidazolin-2-ylhydrazones) of 9,10-anthracenedicarboxaldehyde | AMERICAN CYANAMID COMPANY (US) | 1988-04-27 | — | — | EP | disclosed |
| US-4559349-A | TREATMENT OF PHYCHOSIS | CIBA GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |
| EP-0124476-A1 | Carboxamides, process for their preparation and pharmaceutical preparations containing them | CIBA-GEIGY AG (CH) | 1984-11-07 | — | — | EP | disclosed |
| EP-0019587-B1 | CARBOXYLIC ACID HYDRAZIDES, PROCESS FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-07-20 | — | — | EP | disclosed |
| US-4296128-A | ANTITHROMBOSIS AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-10-20 | — | — | US | disclosed |
| EP-0019587-A1 | Carboxylic acid hydrazides, process for their preparation, their use and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-11-26 | — | — | EP | disclosed |