Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 16/20 | 0.44 |
| ▸ | CBFB | Q13951 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1657596 | 0.86 | GCK (0.45) | GCKCBFBNPC1RAB9ARUNX1 | |
| SCHEMBL1657280 | 0.86 | GCK (0.45) | GCKCBFBNPC1RAB9ARUNX1 | |
| SCHEMBL1659539 | 0.85 | GCK (0.46) | GCKCBFBNPC1RAB9ARUNX1 | |
| SCHEMBL1659552 | 0.83 | GCK (0.46) | GCKCBFBNPC1RAB9ARUNX1 | |
| SCHEMBL1657249 | 0.83 | GCK (0.47) | GCKCBFBNPC1RAB9ARUNX1 | |
| SCHEMBL1656544 | 0.81 | GCK (0.44) | GCKCBFBNPC1RAB9ARUNX1 | |
| SCHEMBL1656342 | 0.81 | GCK (0.41) | GCKCBFBRUNX1 | |
| SCHEMBL1656745 | 0.81 | GCK (0.45) | GCKCBFBNPC1RAB9ARUNX1 | |
| SCHEMBL1656624 | 0.80 | GCK (0.43) | GCKCBFBNPC1RAB9ARUNX1 | |
| SCHEMBL2646318 | 0.80 | CBFB (0.46) | GCKCBFBNPC1RAB9ARUNX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1810969-B1 | ARYLOXY-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | MSD KK (JP) | 2013-08-07 | — | — | EP | disclosed |
| EP-1810969-A1 | ARYLOXY-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-07-25 | — | — | EP | disclosed |