SCHEMBL26433748

SCHEMBL26433748

CC(C)(c1ccccc1)c1ccc(C(C)(C)c2ccc(-c3ccc(-c4cccc(-c5ccc(-c6ccc7c(c6)Sc6ccccc6N7)cc5)c4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 10/20 0.46
GAA P10253 6/20 0.46
MAPT P10636 6/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
MAPK1 P28482 2/20 0.46
CYBB P04839 2/20 0.46
NOX3 Q9HBY0 2/20 0.46
NOX4 Q9NPH5 2/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SNCA P37840 4/20 0.45
CNR1 P21554 3/20 0.45
BCHE P06276 2/20 0.45
ACHE P22303 2/20 0.45
ALOX15 P16050 2/20 0.45
CYP3A4 P08684 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL885158 0.86 NOX1 (0.57) NOX1GAAMAPTMEN1KMT2A
SCHEMBL239282 0.84 NOX1 (0.63) NOX1GAAMAPTMEN1KMT2A
SCHEMBL29674392 0.81 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A
SCHEMBL2139511 0.81 NOX1 (0.49) NOX1GAAMAPTMEN1KMT2A
SCHEMBL7765548 0.80 NOX1 (0.65) NOX1GAAMAPTMEN1KMT2A
Phenothiazine SCHEMBL4173671 0.80 NOX1 (0.71) NOX1GAAMAPTMEN1KMT2A
SCHEMBL5795524 0.80 NOX1 (0.71) NOX1GAAMAPTMEN1KMT2A
SCHEMBL239745 0.80 NOX1 (0.52) NOX1GAAMAPTMEN1KMT2A
SCHEMBL30958692 0.80 NOX1 (0.52) NOX1GAAMAPTMEN1KMT2A
SCHEMBL28091291 0.76 NOX1 (0.64) NOX1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023069896-A1 PROTON-EXCHANGE MEMBRANES FOR ELECTROCHEMICAL REACTIONS UOP LLC (US) 2023-04-27 WO disclosed