Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 14/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437055 | 0.89 | CRBN (0.39) | CRBNDDB1POLB | |
| SCHEMBL26087455 | 0.89 | CRBN (0.39) | CRBNDDB1POLB | |
| SCHEMBL26087612 | 0.89 | CRBN (0.36) | CRBNDDB1POLB | |
| SCHEMBL26436978 | 0.89 | CRBN (0.36) | CRBNDDB1POLB | |
| SCHEMBL26089796 | 0.87 | EPHX1 (0.37) | CRBNDDB1POLB | |
| SCHEMBL26437058 | 0.87 | EPHX1 (0.37) | CRBNDDB1POLB | |
| SCHEMBL30407570 | 0.86 | POLB (0.35) | CRBNDDB1POLB | |
| SCHEMBL31115914 | 0.86 | CRBN (0.33) | CRBNDDB1POLB | |
| SCHEMBL26437151 | 0.86 | CRBN (0.35) | CRBNDDB1POLB | |
| SCHEMBL26435061 | 0.86 | CRBN (0.35) | CRBNDDB1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069708-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |