Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399072 | 0.80 | ABCG2 (0.49) | ABCG2NFE2L2KRASHPGDSMN1; SMN2 | |
| SCHEMBL1399070 | 0.80 | ABCG2 (0.49) | ABCG2NFE2L2KRASHPGDSMN1; SMN2 | |
| SCHEMBL26444949 | 0.77 | ABCG2 (0.46) | ABCG2NFE2L2KRASHPGDSMN1; SMN2 | |
| SCHEMBL6297849 | 0.71 | ABCG2 (0.51) | ABCG2NFE2L2KRASHPGDSMN1; SMN2 | |
| SCHEMBL6297846 | 0.71 | ABCG2 (0.51) | ABCG2NFE2L2KRASHPGDSMN1; SMN2 | |
| SCHEMBL3574506 | 0.71 | ABCG2 (0.59) | ABCG2NFE2L2KRASHPGDSMN1; SMN2 | |
| SCHEMBL3574508 | 0.71 | ABCG2 (0.59) | ABCG2NFE2L2KRASHPGDSMN1; SMN2 | |
| SCHEMBL1399158 | 0.71 | SMN1; SMN2 (0.49) | ABCG2KRASSMN1; SMN2LMNAMAPT | |
| SCHEMBL1399161 | 0.71 | SMN1; SMN2 (0.49) | ABCG2KRASSMN1; SMN2LMNAMAPT | |
| SCHEMBL1226433 | 0.70 | ABCG2 (0.58) | ABCG2NFE2L2KRASHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230139056-A1 | METHODS, COMPOSITIONS AND REAGENTS FOR PREPARING COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2023-05-04 | — | — | US | disclosed |