Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 15/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645659 | 0.94 | GCK (0.51) | GCKCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2645131 | 0.90 | GCK (0.45) | GCKCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2646436 | 0.89 | GCK (0.45) | GCKCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2645390 | 0.88 | GCK (0.44) | GCKCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2644602 | 0.88 | GCK (0.48) | GCKCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2645204 | 0.87 | GCK (0.45) | GCKCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2643903 | 0.87 | GCK (0.45) | GCKCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2645266 | 0.87 | GCK (0.45) | GCKCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2644349 | 0.87 | GCK (0.46) | GCKCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2644466 | 0.86 | GCK (0.42) | GCKCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1702919-B1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-05-30 | — | — | EP | disclosed |
| EP-1702919-A1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |