Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 14/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647178 | 0.86 | GCK (0.42) | GCKDHODHCBFBATRNPBWR1 | |
| SCHEMBL2644522 | 0.86 | GCK (0.48) | GCKDHODHCBFB | |
| SCHEMBL2646272 | 0.85 | GCK (0.56) | GCKCBFB | |
| SCHEMBL2646084 | 0.85 | GCK (0.56) | GCKCBFB | |
| SCHEMBL2644895 | 0.85 | GCK (0.42) | GCKDHODHCBFBATRNPBWR1 | |
| SCHEMBL2648299 | 0.84 | GCK (0.46) | GCKDHODHCBFB | |
| SCHEMBL2646054 | 0.81 | DHODH (0.41) | GCKDHODHCBFBNPBWR1 | |
| SCHEMBL2643513 | 0.77 | GCK (0.46) | GCKCBFB | |
| SCHEMBL2646884 | 0.76 | GCK (0.43) | GCKDHODHCBFB | |
| SCHEMBL2653649 | 0.74 | GCK (0.51) | GCKCBFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1702919-B1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-05-30 | — | — | EP | disclosed |
| EP-1702919-A1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |