SCHEMBL2644589

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2644770	0.91	GCK (0.46)	GCKLPAR1LPAR5FFAR1EZH2
	SCHEMBL644290	0.89	GCK (0.51)	GCKLPAR1LPAR5HIF1A
	SCHEMBL644377	0.89	GCK (0.52)	GCKLPAR1LPAR5FFAR1EZH2
	SCHEMBL2644922	0.85	GCK (0.72)	GCKS1PR2
	SCHEMBL2643802	0.84	GCK (0.48)	GCKLPAR1LPAR5EZH2RXRA
	SCHEMBL645237	0.83	GCK (0.71)	GCK
	SCHEMBL645334	0.83	GCK (0.78)	GCKF10
	SCHEMBL2644367	0.83	GCK (0.51)	GCK
	SCHEMBL645314	0.81	GCK (0.43)	GCKLPAR1LPAR5HIF1A
	SCHEMBL2643750	0.80	GCK (0.49)	GCKLPAR1LPAR5EZH2RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.