SCHEMBL2644769

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2644938	0.97	GCK (0.55)	GCKEZH2HRH3RAB9AL3MBTL1
	SCHEMBL2643938	0.88	GCK (0.59)	GCKEZH2LPAR1LPAR5ALDH1A1
	SCHEMBL2645431	0.88	GCK (0.58)	GCKEZH2LPAR1LPAR5ALDH1A1
	SCHEMBL2643748	0.86	GCK (0.54)	GCKEZH2LPAR1LPAR5ALDH1A1
	SCHEMBL2643773	0.86	GCK (0.54)	GCKEZH2LPAR1LPAR5ALDH1A1
	SCHEMBL644210	0.85	GCK (0.78)	GCKEZH2HRH3
	SCHEMBL2644107	0.85	GCK (0.56)	GCKEZH2LPAR1LPAR5ALDH1A1
	SCHEMBL2644110	0.85	GCK (0.54)	GCKEZH2RAB9APKMLPAR1
	SCHEMBL2644082	0.83	GCK (0.53)	GCKEZH2LPAR1LPAR5ALDH1A1
	SCHEMBL2645491	0.83	GCK (0.56)	GCKEZH2LPAR1LPAR5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.