Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 13/20 | 0.74 |
| ▸ | PIM1 | P11309 | 5/20 | 0.74 |
| ▸ | DYRK2 | Q92630 | 7/20 | 0.71 |
| ▸ | CCND1 | P24385 | 8/20 | 0.67 |
| ▸ | CDK4 | P11802 | 8/20 | 0.67 |
| ▸ | CCND3 | P30281 | 6/20 | 0.67 |
| ▸ | CDK2 | P24941 | 6/20 | 0.65 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.65 |
| ▸ | CDK9 | P50750 | 4/20 | 0.65 |
| ▸ | CDK1 | P06493 | 4/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.65 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.65 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.64 |
| ▸ | CDK7 | P50613 | 2/20 | 0.64 |
| ▸ | CCNH | P51946 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29754565 | 0.99 | CDK6 (0.73) | CDK6PIM1DYRK2CCND1CDK4 | |
| Hydrochloric Acid SCHEMBL28521115 | 0.99 | CDK6 (0.73) | CDK6PIM1DYRK2CCND1CDK4 | |
| SCHEMBL26447876 | 0.86 | DYRK2 (0.86) | CDK6DYRK2CCND1CDK4CCND3 | |
| SCHEMBL29754350 | 0.86 | DYRK2 (0.86) | CDK6DYRK2CCND1CDK4CCND3 | |
| Hydrochloric Acid SCHEMBL29754482 | 0.85 | DYRK2 (0.87) | CDK6DYRK2CCND1 | |
| Hydrochloric Acid SCHEMBL26680019 | 0.85 | DYRK2 (0.87) | CDK6DYRK2CCND1 | |
| Hydrochloric Acid SCHEMBL29414485 | 0.84 | CDK6 (0.98) | CDK6PIM1DYRK2CCND1CDK4 | |
| Hydrochloric Acid SCHEMBL28586621 | 0.84 | CDK6 (0.98) | CDK6PIM1DYRK2CCND1CDK4 | |
| SCHEMBL26447969 | 0.84 | DYRK2 (0.83) | CDK6PIM1DYRK2CCND1CDK4 | |
| SCHEMBL26447882 | 0.84 | DYRK2 (0.98) | CDK6PIM1DYRK2CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282864-A1 | CDK6/DYRK2 DUAL-TARGET INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Tasly Diyi Pharmaceutical Co., Ltd. (CN) | 2023-11-29 | — | — | EP | disclosed |
| US-20230303553-A1 | CDK6/DYRK2 DUAL-TARGET INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303553-A1 | CDK6/DYRK2 DUAL-TARGET INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CDK6, DYRK2, CDK16 | CDK6 1/4885PIM1 393/4885DYRK2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.