Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.87 |
| ▸ | STAT3 | P40763 | 4/20 | 0.87 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23754805 | 0.93 | TYK2 (1.00) | TYK2STAT3PDE4D | |
| SCHEMBL26448077 | 0.81 | TYK2 (0.59) | TYK2STAT3PDE4D | |
| SCHEMBL24224247 | 0.80 | TYK2 (0.78) | TYK2STAT3PDE4D | |
| SCHEMBL22092669 | 0.80 | TYK2 (0.78) | TYK2STAT3PDE4D | |
| SCHEMBL24224248 | 0.80 | TYK2 (0.78) | TYK2STAT3PDE4D | |
| SCHEMBL21887515 | 0.80 | TYK2 (0.84) | TYK2STAT3PDE4D | |
| SCHEMBL21811321 | 0.80 | TYK2 (0.84) | TYK2STAT3PDE4D | |
| SCHEMBL21811186 | 0.80 | TYK2 (0.84) | TYK2STAT3PDE4D | |
| SCHEMBL30349300 | 0.80 | TYK2 (0.84) | TYK2STAT3PDE4D | |
| SCHEMBL23754756 | 0.80 | TYK2 (0.68) | TYK2STAT3PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136885-A1 | SUBSTITUTED 7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES | ELI LILLY AND COMPANY | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136885-A1 | SUBSTITUTED 7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES | SSB, IL1R1, SLC5A1 | TYK2 270/4885STAT3 100/4885PDE4D 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.