SCHEMBL2645182

SCHEMBL2645182

CS(=O)(=O)c1ccc(Oc2cc3nc(-c4cnccn4)[nH]c3cc2C2C(=O)CCN2C(=O)C(F)(F)F)cc1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2646489 0.87 GCK (0.69) GCK
SCHEMBL2644852 0.80 GCK (0.82) GCK
SCHEMBL2646921 0.78 GCK (0.84) GCK
SCHEMBL2643891 0.78 GCK (0.63) GCK
SCHEMBL2645693 0.78 GCK (0.63) GCK
SCHEMBL2644331 0.75 GCK (0.56) GCK
SCHEMBL1656399 0.75 GCK (0.69) GCK
SCHEMBL8533172 0.74 GCK (0.62) GCK
SCHEMBL1659318 0.74 GCK (0.71) GCK
SCHEMBL2654726 0.73 GCK (0.82) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1702919-B1 NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE MSD KK (JP) 2012-05-30 EP disclosed
EP-1702919-A1 NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-09-20 EP disclosed