Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 16/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2646965 | 0.88 | GCK (0.41) | GCKDHODHJMJD6PARP1 | |
| SCHEMBL2655098 | 0.87 | DHODH (0.35) | GCKDHODH | |
| SCHEMBL2645953 | 0.87 | GCK (0.44) | GCK | |
| SCHEMBL2645403 | 0.87 | CBFB (0.43) | GCK | |
| SCHEMBL2645709 | 0.87 | GCK (0.39) | GCKDHODH | |
| SCHEMBL2644818 | 0.83 | GCK (0.42) | GCK | |
| SCHEMBL3541075 | 0.82 | GCK (0.42) | GCK | |
| SCHEMBL2645611 | 0.79 | GCK (0.45) | GCK | |
| SCHEMBL2646268 | 0.77 | GCK (0.40) | GCK | |
| SCHEMBL2644582 | 0.75 | CBFB (0.44) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1702919-B1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-05-30 | — | — | EP | disclosed |
| EP-1702919-A1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |