SCHEMBL26454154

SCHEMBL26454154

CC(C)c1ccc([Si](C)(C)C(C)(C)C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.47
NR1H3 Q13133 1/20 0.47
NOTUM Q6P988 4/20 0.37
TYR P14679 2/20 0.37
CYP2C9 P11712 2/20 0.35
CYP2D6 P10635 1/20 0.35
HIF1A Q16665 1/20 0.35
HTT P42858 1/20 0.34
PTPN5 P54829 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
IDO1 P14902 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
NFKB1 P19838 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
NISCH Q9Y2I1 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15715723 0.79 IDO1 (0.33) NR1H2NR1H3NOTUMTYRCYP2C9
SCHEMBL29308143 0.78 PTPN5 (0.36) NR1H2NR1H3NOTUMTYRCYP2C9
SCHEMBL19257000 0.77 NR1H2 (0.47) NR1H2NR1H3
SCHEMBL18913902 0.76 NR1H2 (0.50) NR1H2NR1H3CYP2D6HIF1ANPC1
SCHEMBL196876 0.76 NR1H2 (0.50) NR1H2NR1H3NOTUMCYP2D6HIF1A
SCHEMBL26800453 0.76 PTPN5 (0.37) NOTUMTYRCYP2C9CYP2D6HIF1A
SCHEMBL6124152 0.75 TYR (0.42) NR1H2NR1H3NOTUMTYRCYP2C9
SCHEMBL13084774 0.75 TYR (0.42) NOTUMTYRCYP2C9CYP2D6HIF1A
SCHEMBL19256277 0.75 NR1H2 (0.54) NR1H2NR1H3
SCHEMBL988411 0.73 NR1H2 (0.52) NR1H2NR1H3NOTUMNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230137110-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-05-04 US disclosed
CN-109134267-B Synthetic method of aromatic amine compound 北京大学 2020-11-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230137110-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF SLCO2B1, SLCO2A1, SLCO1B3 NR1H2 4322/4885NR1H3 3938/4885NOTUM 3106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.