Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 16/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | CBFB | Q13951 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645069 | 0.92 | GCK (0.44) | GCKMETAP2CBFB | |
| SCHEMBL2646436 | 0.92 | GCK (0.45) | GCKMETAP2 | |
| SCHEMBL2645526 | 0.91 | GCK (0.52) | GCKMETAP2CBFB | |
| SCHEMBL2647109 | 0.91 | GCK (0.45) | GCKMETAP2CBFB | |
| SCHEMBL2645910 | 0.90 | GCK (0.44) | GCKMETAP2CBFB | |
| SCHEMBL2645745 | 0.90 | GCK (0.53) | GCKMETAP2CBFB | |
| SCHEMBL2648205 | 0.90 | GCK (0.45) | GCKMETAP2CBFB | |
| SCHEMBL2646005 | 0.89 | GCK (0.43) | GCKMETAP2CBFB | |
| SCHEMBL2646322 | 0.89 | GCK (0.46) | GCKMETAP2CBFB | |
| SCHEMBL2646884 | 0.88 | GCK (0.43) | GCKMETAP2CBFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1702919-B1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-05-30 | — | — | EP | disclosed |
| US-7728025-B2 | 2-heteroaryl-substituted benzimidazole derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| EP-1702919-A1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |