⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268482 | 1.00 | — | — | |
| SCHEMBL11744140 | 0.96 | — | — | |
| Thiophene SCHEMBL11745345 | 0.77 | — | — | |
| Thiophene SCHEMBL11796434 | 0.77 | — | — | |
| SCHEMBL1841946 | 0.61 | — | — | |
| SCHEMBL1841948 | 0.61 | — | — | |
| SCHEMBL9361504 | 0.61 | — | — | |
| SCHEMBL8082612 | 0.61 | — | — | |
| SCHEMBL4526279 | 0.61 | — | — | |
| SCHEMBL4745890 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551857-A | Imidazopyrimidinone compounds as pesticides | 巴斯夫欧洲公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-105745209-B | Triazolopyridine compounds, compositions, and methods of use thereof | 豪夫迈·罗氏有限公司 | 2018-10-23 | — | — | CN | disclosed |
| EP-2594555-B1 | HETEROCYCLIC COMPOUND, AND p27 KIP1 DEGRADATION INHIBITOR | ASKA PHARM CO LTD (JP) | 2018-03-07 | — | — | EP | disclosed |
| US-9200008-B2 | Heterocyclic compound and p27Kip1 degradation inhibitor | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2015-12-01 | — | — | US | disclosed |
| EP-2594555-A1 | HETEROCYCLIC COMPOUND, AND p27 KIP1 DEGRADATION INHIBITOR | ASKA Pharmaceutical Co., Ltd. (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-20130079306-A1 | HETEROCYCLIC COMPOUND AND p27Kip1 DEGRADATION INHIBITOR | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-28 | — | — | US | disclosed |
| EP-1572670-B1 | 5-SUBSTITUTED-PYRAZINE OR -PYRIDINE GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2007-08-22 | — | — | EP | disclosed |
| US-7132425-B2 | 5-substituted-six-membered heteroaromatic glucokinase activators | HOFFMANN-LA ROCHE INC. (US) | 2006-11-07 | — | — | US | disclosed |
| EP-1572670-A1 | 5-SUBSTITUTED-PYRAZINE OR -PYRIDINE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| CN-1171863-C | Carbamate derivatives and agricultural/horticultural bactericides | ��Ԩ��ѧ��ҵ��ʽ���� | 2004-10-20 | — | — | CN | disclosed |
| US-20040147748-A1 | 5-Substituted-six-membered heteroaromatic glucokinase activators | CHEN SHAOQING (US) | 2004-07-29 | — | — | US | disclosed |
| WO-2004052869-A1 | 5-SUBSTITUTED-PYRAZINE OR PYRIDINE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-24 | — | — | WO | disclosed |
| CN-1368956-A | Carbamate derivatives and agricultural/horticultural bactericides | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2002-09-11 | — | — | CN | disclosed |
| WO-1992004349-A1 | THERAPEUTIC AGENTS | PFIZER LIMITED (GB) | 1992-03-19 | — | — | WO | disclosed |
| EP-0122231-B1 | HERBICIDAL AGENT | CIBA-GEIGY AG (CH) | 1990-01-17 | — | — | EP | disclosed |
| EP-0122231-A2 | Herbicidal agent | CIBA-GEIGY AG (CH) | 1984-10-17 | — | — | EP | disclosed |
| US-4334087-A | FROM AN OXIMINOHALIDE | ZOECON CORPORATION (US) | 1982-06-08 | — | — | US | disclosed |
| US-4327213-A | ANTIULCER AGENTS | ACF Chemiefarma VA (NL) | 1982-04-27 | — | — | US | disclosed |