Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 16/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 16/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 11/20 | 0.75 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.75 |
| ▸ | CASP3 | P42574 | 2/20 | 0.75 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.75 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.75 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | CRHBP | P24387 | 1/20 | 0.67 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12008539 | 0.84 | KMT2A (0.72) | MEN1KMT2AMAPK1MAPTALDH1A1 | |
| SCHEMBL17762653 | 0.82 | MEN1 (0.70) | MEN1KMT2AMAPK1MAPTALDH1A1 | |
| SCHEMBL23752553 | 0.80 | MEN1 (1.00) | MEN1KMT2AMAPK1MAPTALDH1A1 | |
| SCHEMBL23752554 | 0.80 | MEN1 (1.00) | MEN1KMT2AMAPK1MAPTALDH1A1 | |
| SCHEMBL12010971 | 0.80 | MEN1 (1.00) | MEN1KMT2AMAPK1MAPTALDH1A1 | |
| SCHEMBL5459723 | 0.80 | MEN1 (0.87) | MEN1KMT2AMAPK1MAPTALDH1A1 | |
| SCHEMBL5459720 | 0.80 | MEN1 (0.87) | MEN1KMT2AMAPK1MAPTALDH1A1 | |
| SCHEMBL18103056 | 0.79 | MEN1 (1.00) | MEN1KMT2AMAPK1MAPTALDH1A1 | |
| SCHEMBL2080496 | 0.78 | MEN1 (0.82) | MEN1KMT2AMAPK1MAPTALDH1A1 | |
| SCHEMBL2080494 | 0.78 | MEN1 (0.82) | MEN1KMT2AMAPK1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230364057-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2023-11-16 | — | — | US | disclosed |
| US-20230136466-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230364057-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | TOP1, DNA2, TOP2A | MEN1 4457/4885KMT2A 2037/4885MAPK1 2960/4885 |
| US-20230136466-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | TOP1, DNA2, TOP2A | MEN1 4457/4885KMT2A 2037/4885MAPK1 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.