Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 17/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2646258 | 0.96 | CYP19A1 (0.35) | SLC22A12DHODHGCKCYP19A1 | |
| SCHEMBL2645416 | 0.93 | DHODH (0.41) | DHODHGCKCYP19A1 | |
| SCHEMBL2644099 | 0.89 | GCK (0.36) | DHODHGCK | |
| SCHEMBL2643771 | 0.87 | GCK (0.34) | SLC22A12DHODHGCKCYP19A1 | |
| SCHEMBL2645048 | 0.86 | GCK (0.37) | DHODHGCK | |
| SCHEMBL2646359 | 0.86 | CBFB (0.43) | DHODHGCK | |
| SCHEMBL2646807 | 0.85 | GCK (0.36) | DHODHGCK | |
| SCHEMBL2646069 | 0.85 | DHODH (0.42) | SLC22A12DHODHGCKCYP19A1 | |
| SCHEMBL2643868 | 0.83 | GCK (0.37) | DHODHGCK | |
| SCHEMBL2645487 | 0.83 | GCK (0.37) | DHODHGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1702919-B1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-05-30 | — | — | EP | disclosed |
| EP-1702919-A1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |