SCHEMBL26464150

SCHEMBL26464150

FC(F)(F)Oc1ccc(-c2nc(-c3ccc(Cl)cc3)c[nH]2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.50
DHODH Q02127 2/20 0.45
CHRNA7 P36544 2/20 0.45
SCN5A Q14524 5/20 0.40
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
RAB9A P51151 1/20 0.39
CCNT1 O60563 1/20 0.38
CCNA2 P20248 1/20 0.38
CDK2 P24941 1/20 0.38
CDK9 P50750 1/20 0.38
NISCH Q9Y2I1 1/20 0.38
GRK6 P43250 1/20 0.38
MAPK1 P28482 1/20 0.38
RECQL P46063 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ACLY P53396 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26464281 0.86 TRPV1 (0.41) ALOX5CHRNA7SCN5AMAPTKDM4E
SCHEMBL3401143 0.86 CCNT1 (0.43) SCN5AMAPTKDM4ENPC1ALDH1A1
SCHEMBL26096161 0.83 GRK6 (0.39) CHRNA7SCN5AMAPTKDM4ENPC1
SCHEMBL7137198 0.83 KDM4E (0.46) ALOX5MAPTKDM4ENPC1ALDH1A1
SCHEMBL3401595 0.81 AURKA (0.50) DHODHKDM4ENPC1ALDH1A1RAB9A
SCHEMBL26464174 0.81 PDGFRB (0.47) ALOX5MAPTKDM4ENPC1ALDH1A1
SCHEMBL7135272 0.81 PDGFRB (0.47) ALOX5MAPTKDM4ENPC1ALDH1A1
SCHEMBL7142074 0.79 MAPK13 (0.46) DHODHMAPTKDM4ENPC1ALDH1A1
SCHEMBL26465207 0.78 ABL1 (0.51) SCN5AMAPTKDM4ENPC1ALDH1A1
Hydrochloric Acid SCHEMBL7142932 0.77 MAPK13 (0.44) DHODHMAPTKDM4ENPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023073115-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-04 WO disclosed
EP-4173485-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-03 EP disclosed