Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30494267 | 0.84 | PRMT5 (0.53) | ABL1PRMT5WDR77CYP11B1CYP11B2 | |
| SCHEMBL30494281 | 0.79 | ABL1 (0.59) | ABL1PRMT5WDR77CYP11B1CYP11B2 | |
| SCHEMBL26464927 | 0.79 | ABL1 (0.59) | ABL1PRMT5WDR77CYP11B1CYP11B2 | |
| SCHEMBL10273624 | 0.75 | ABL1 (0.55) | ABL1PRMT5WDR77CYP11B1CYP11B2 | |
| SCHEMBL26463262 | 0.75 | ABL1 (0.55) | ABL1PRMT5WDR77CYP11B1CYP11B2 | |
| SCHEMBL30494340 | 0.75 | ABL1 (0.55) | ABL1PRMT5WDR77CYP11B1CYP11B2 | |
| SCHEMBL26464740 | 0.74 | CYP11B1 (0.58) | ABL1PRMT5WDR77CYP11B1CYP11B2 | |
| SCHEMBL13456619 | 0.73 | SLC6A2 (0.44) | SLC6A2SLC6A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25455050 | 0.73 | MAP4K4 (0.49) | PRMT5WDR77SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL11267771 | 0.72 | ABL1 (0.58) | ABL1PRMT5WDR77CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072026-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-05-04 | — | — | WO | disclosed |