Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.46 |
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22791722 | 0.95 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL26468398 | 0.94 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL24032227 | 0.91 | NPC1 (0.42) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL22791664 | 0.90 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL26468243 | 0.90 | NPC1 (0.45) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL24032654 | 0.89 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL26466101 | 0.88 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL26465029 | 0.88 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL25012369 | 0.88 | NPC1 (0.43) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL26465455 | 0.88 | NPC1 (0.36) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023071073-A1 | ARYLAMINE ORGANIC COMPOUND AND USE THEREOF | 广州华睿光电材料有限公司 | 2023-05-04 | — | — | WO | disclosed |