Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660365 | 0.89 | GCK (1.00) | GCK | |
| SCHEMBL2642443 | 0.86 | GCK (0.62) | GCK | |
| SCHEMBL2642301 | 0.79 | GCK (0.80) | GCK | |
| SCHEMBL2642428 | 0.78 | GCK (1.00) | GCK | |
| SCHEMBL2642583 | 0.78 | GCK (1.00) | GCK | |
| SCHEMBL2642419 | 0.76 | GCK (0.78) | GCK | |
| SCHEMBL2642176 | 0.76 | GCK (0.78) | GCK | |
| SCHEMBL2642277 | 0.76 | GCK (0.83) | GCK | |
| SCHEMBL2642606 | 0.76 | GCK (0.75) | GCK | |
| SCHEMBL2642335 | 0.76 | GCK (0.71) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687502-B2 | Substituted quinazoline or pyridopyrimidine derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| EP-1734040-A1 | SUBSTITUTED QUINAZOLINE OR PYRIDOPYRIMIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-12-20 | — | — | EP | disclosed |