⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26467582 | 0.86 | — | — | |
| SCHEMBL26466565 | 0.86 | — | — | |
| SCHEMBL26100404 | 0.86 | — | — | |
| SCHEMBL26470269 | 0.86 | — | — | |
| SCHEMBL26465885 | 0.84 | NR1H2 (0.33) | — | |
| SCHEMBL26465916 | 0.84 | NR1H2 (0.33) | — | |
| SCHEMBL26099256 | 0.81 | — | — | |
| SCHEMBL30070864 | 0.81 | — | — | |
| SCHEMBL26096030 | 0.79 | — | — | |
| SCHEMBL26097594 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140132-A1 | ARGINASE INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2023-05-04 | — | — | US | disclosed |