Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754493 | 0.89 | CYP3A4 (0.54) | CYP3A4ADRA2AALDH1A1LMNAHTT | |
| SCHEMBL6245212 | 0.80 | CYP3A4 (0.64) | CYP3A4ADRA2AALDH1A1LMNAHTT | |
| SCHEMBL1758444 | 0.77 | CYP2C9 (0.53) | CYP3A4ALDH1A1LMNAHTTKDM4E | |
| SCHEMBL1758445 | 0.77 | CYP2C9 (0.53) | CYP3A4ALDH1A1LMNAHTTKDM4E | |
| SCHEMBL23644547 | 0.75 | KMT2A (0.33) | ALDH1A1GAAPOLBKMT2A | |
| SCHEMBL23644548 | 0.75 | KMT2A (0.33) | ALDH1A1GAAPOLBKMT2A | |
| SCHEMBL21131297 | 0.74 | CYP3A4 (0.62) | CYP3A4ADRA2AALDH1A1LMNAHTT | |
| SCHEMBL8292092 | 0.74 | CYP3A4 (0.62) | CYP3A4ADRA2AALDH1A1LMNAHTT | |
| SCHEMBL11858266 | 0.74 | CYP3A4 (0.49) | CYP3A4ADRA2AALDH1A1LMNAHTT | |
| SCHEMBL7093426 | 0.73 | CYP3A4 (0.56) | CYP3A4ADRA2AALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073559-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| WO-2023076237-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |