Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | CASP3 | P42574 | 3/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465658 | 0.93 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9ACASP3SENP7 | |
| SCHEMBL26465279 | 0.92 | NPC1 (0.44) | SMN1; SMN2NPC1RAB9ACASP3SENP7 | |
| SCHEMBL23667824 | 0.92 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9ACASP3SENP7 | |
| SCHEMBL23667806 | 0.92 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9ACASP3SENP7 | |
| SCHEMBL26465653 | 0.91 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9ACASP3SENP7 | |
| SCHEMBL25524734 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9ACASP3SENP7 | |
| SCHEMBL24550906 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9ACASP3SENP7 | |
| SCHEMBL24553247 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9ACASP3SENP7 | |
| SCHEMBL26465683 | 0.89 | MAPT (0.39) | SMN1; SMN2NPC1RAB9ACASP3SENP7 | |
| SCHEMBL25525205 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9ACASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023071073-A1 | ARYLAMINE ORGANIC COMPOUND AND USE THEREOF | 广州华睿光电材料有限公司 | 2023-05-04 | — | — | WO | disclosed |