SCHEMBL2646818

SCHEMBL2646818

CN1CCC(c2cc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 2/20 1.00
GCGR P47871 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3290870 1.00 MAPK14 (1.00) MAPK14GCGR
SCHEMBL22589338 0.88 MAPK14 (0.79) MAPK14
SCHEMBL5726974 0.87 MAPK14 (0.78) MAPK14
SCHEMBL22589279 0.86 MAPK14 (0.76) MAPK14
SCHEMBL22589331 0.86 MAPK14 (0.76) MAPK14
SCHEMBL7621334 0.86 MAPK14 (0.75) MAPK14
SCHEMBL22589187 0.85 MAPK14 (0.74) MAPK14
SCHEMBL22589150 0.85 MAPK14 (0.74) MAPK14GCGR
SCHEMBL22589305 0.85 MAPK14 (0.74) MAPK14GCGR
SCHEMBL22589148 0.85 MAPK14 (0.74) MAPK14GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102311425-B Anticoccidiosis compound and preparation method as well as application thereof CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD 2013-06-05 CN claimed
CN-102311425-A Anticoccidiosis compound and preparation method as well as application thereof CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD 2012-01-11 CN claimed
EP-0859771-A4 SUBSTITUTED PYRIDYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE MERCK & CO INC (US) 2000-03-15 EP claimed
EP-0859771-A1 SUBSTITUTED PYRIDYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE Merck & Co., Inc. (US) 1998-08-26 EP claimed
US-5776954-A GLUCAGON ANTAGONISTS MERCK & CO., INC. (US) 1998-07-07 US claimed
WO-1997016442-A1 SUBSTITUTED PYRIDYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE MERCK & CO., INC. (US) 1997-05-09 WO claimed
CN-102311425-B Anticoccidiosis compound and preparation method as well as application thereof CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD 2013-06-05 CN disclosed
CN-102311425-A Anticoccidiosis compound and preparation method as well as application thereof CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD 2012-01-11 CN disclosed
US-5776954-A GLUCAGON ANTAGONISTS MERCK & CO., INC. (US) 1998-07-07 US disclosed
WO-1997016442-A1 SUBSTITUTED PYRIDYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE MERCK & CO., INC. (US) 1997-05-09 WO disclosed