Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.53 |
| ▸ | IKZF2 | Q9UKS7 | 7/20 | 0.48 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30373047 | 0.92 | CRBN (0.50) | CRBNIKZF2GSPT1CSNK1A1 | |
| SCHEMBL30373201 | 0.86 | CRBN (0.55) | CRBNIKZF2GSPT1CSNK1A1 | |
| SCHEMBL26469968 | 0.84 | CRBN (0.54) | CRBNIKZF2GSPT1 | |
| SCHEMBL26474350 | 0.84 | CRBN (0.54) | CRBNIKZF2GSPT1 | |
| SCHEMBL26091605 | 0.84 | CRBN (0.63) | CRBNGSPT1CSNK1A1 | |
| SCHEMBL26740556 | 0.81 | CRBN (0.56) | CRBNIKZF2GSPT1CSNK1A1 | |
| SCHEMBL30373512 | 0.81 | CRBN (0.55) | CRBNIKZF2GSPT1CSNK1A1 | |
| SCHEMBL26470350 | 0.81 | CRBN (0.55) | CRBNIKZF2GSPT1CSNK1A1 | |
| SCHEMBL30373640 | 0.79 | CRBN (0.57) | CRBNGSPT1CSNK1A1 | |
| SCHEMBL26470352 | 0.79 | CRBN (0.57) | CRBNGSPT1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069720-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |