Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CCR8 | P51685 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | C1R | P00736 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224301 | 0.76 | HSD17B10 (0.61) | KDM4ESMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL23300924 | 0.76 | KDM4E (0.61) | KDM4ESMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL29933981 | 0.76 | KDM4E (0.61) | KDM4ESMN1; SMN2HSD17B10KMT2ACCR8 | |
| SCHEMBL15252375 | 0.76 | KDM4E (0.61) | KDM4ESMN1; SMN2HSD17B10KMT2ACCR8 | |
| SCHEMBL8130015 | 0.75 | KDM4E (0.59) | KDM4ESMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL8133180 | 0.74 | KDM4E (0.59) | KDM4ESMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL6363004 | 0.74 | HSD17B10 (0.59) | KDM4ESMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL6363005 | 0.74 | HSD17B10 (0.59) | KDM4ESMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL593971 | 0.73 | KDM4E (0.58) | KDM4ESMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL1245388 | 0.73 | CCR8 (0.61) | KDM4ESMN1; SMN2HSD17B10KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072273-A1 | POLYCYCLIC COMPOUND AS CBL-B INHIBITOR | 先声再明医药有限公司 | 2023-05-04 | — | — | WO | disclosed |