SCHEMBL2648522

SCHEMBL2648522

CC(C)c1nc(C(C)C)c(CC=CCc2ccccc2)c(-c2ccc(F)cc2)c1CO

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2649717 0.87 GCGR (0.62) GCGR
SCHEMBL2648032 0.87 GCGR (0.62) GCGR
SCHEMBL2648671 0.85 GCGR (0.70) GCGR
SCHEMBL2649028 0.84 GCGR (0.73) GCGR
SCHEMBL2647829 0.84 GCGR (0.64) GCGR
SCHEMBL8949822 0.83 GCGR (0.88) GCGR
SCHEMBL2652307 0.82 GCGR (0.76) GCGR
SCHEMBL2655816 0.82 GCGR (0.74) GCGR
SCHEMBL2647526 0.82 GCGR (0.73) GCGR
SCHEMBL6958229 0.81 GCGR (0.70) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0934274-A1 SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS Bayer Corporation (US) 1999-08-11 EP disclosed
WO-1998004528-A2 SUBSTITUTED PYRIDINES AND BIPHENYLS AS ANTI-HYPERCHOLESTERINEMIC, ANTI-HYPERLIPOPROTEINEMIC AND ANTI-HYPERGLYCEMIC AGENTS BAYER CORPORATION (US) 1998-02-05 WO disclosed