Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26492006 | 0.92 | CASR (0.49) | CASRTLR8PIN1PDE4BPGR | |
| SCHEMBL26486334 | 0.88 | CASR (0.61) | CASRTLR8PIN1PDE4BPGR | |
| SCHEMBL26492001 | 0.87 | CASR (0.45) | CASRTLR8PIN1PDE4BPGR | |
| SCHEMBL26486238 | 0.86 | CASR (0.48) | CASRTLR8PIN1PDE4BPGR | |
| SCHEMBL26486327 | 0.85 | CASR (0.47) | CASRTLR8PIN1PDE4BPGR | |
| SCHEMBL26486331 | 0.85 | CASR (0.47) | CASRPIN1PDE4BPGRRORA | |
| SCHEMBL26492004 | 0.84 | CASR (0.61) | CASRTLR8PIN1PDE4BPGR | |
| SCHEMBL26491993 | 0.84 | CASR (0.46) | CASRTLR8PIN1PDE4BPGR | |
| SCHEMBL26486222 | 0.82 | TLR8 (0.45) | CASRTLR8TP53KDM4EALDH1A1 | |
| SCHEMBL29832325 | 0.82 | CASR (0.43) | CASRTLR8PDE4BPGRRORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022183008-A9 | AMINO-BENZIMIDAZOLE CATALYSTS FOR THE PREPARATION OF POLYOLEFINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-10-12 | — | — | WO | disclosed |