Fluoride

Fluoride

SCHEMBL2648816

C[SiH](C)C.F.F

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27521922 1.00
SCHEMBL29016 0.89
Charcoal, Activated SCHEMBL7199313 0.80
SCHEMBL8967414 0.80
Hydrochloric Acid SCHEMBL106021 0.80
Hydrogen Sulfide SCHEMBL1674715 0.80
Hydrogen Sulfide SCHEMBL11460325 0.80
SCHEMBL9223832 0.80
SCHEMBL2798309 0.80
Helium SCHEMBL20953787 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110943250-B Electrolyte and lithium ion battery containing electrolyte 宁德新能源科技有限公司 2021-09-24 CN claimed
CN-110943250-A Electrolyte and lithium ion battery containing electrolyte 宁德新能源科技有限公司 2020-03-31 CN claimed
EP-3109244-A2 PREPARATION OF 2'FLUORO-2'-ALKYL-SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES Gilead Pharmasset LLC (US) 2016-12-28 EP claimed
CN-101437524-A Preparation of 2 '-fluoro-2' -alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and derivatives thereof PHARMASSET INC (US) 2009-05-20 CN claimed
EP-1809301-A2 PREPARATION OF 2'FLUORO-2'-ALKYL-SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES Pharmasset, Inc. (US) 2007-07-25 EP claimed
US-20060122146-A1 Preparation of 2'-fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives GILEAD SCIENCES, INC. 2006-06-08 US claimed
WO-2006031725-A2 PREPARATION OF 2'­FLUORO-2'- ALKYL- SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES PHARMASSET, INC. (US) 2006-03-23 WO claimed
US-6180718-B1 REACTING (HETERO)ARYLLITHIUM WITH A DICHLOROSILANE, THEN REACTING RESULTING ARYL-CHLOROSILANE WITH A SOLID-SUPPORTED HYDROXYL GROUP TO FORM A SILYL ETHER LINKAGE, THEN REACTING SUPPORTED MOLECULES TO FORM DRUGS OR AGROCHEMICALS WARNER-LAMBERT COMPANY 2001-01-30 US claimed
WO-1997031880-A1 PROCESS FOR PREPARATION OF AROMATIC AND HETEROAROMATIC MOLECULES WARNER-LAMBERT COMPANY (US) 1997-09-04 WO claimed
US-5466877-A Fluorination with deesterification and alkylation MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-14 US claimed
WO-1995025082-A1 PROCESS FOR CONVERTING PERFLUORINATED ESTERS TO PERFLUORINATED ACYL FLUORIDES AND/OR KETONES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-09-21 WO claimed
CN-110943250-B Electrolyte and lithium ion battery containing electrolyte 宁德新能源科技有限公司 2021-09-24 CN disclosed
CN-107949562-B Positive allosteric modulators of muscarinic M2 receptors 拜耳制药股份公司 2021-07-23 CN disclosed
CN-107383002-B Fluorine-containing triazole pyridine compounds, and preparation method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2021-07-13 CN disclosed
EP-3300500-B9 TRIAZOLE AGONISTS OF THE APJ RECEPTOR AMGEN INC (US) 2021-01-13 EP disclosed
US-5130320-A Chemical intermediates MONSANTO COMPANY (US) 1992-07-14 US disclosed
US-5128347-A (De)etherification, hydrolysis MONSANTO COMPANY (US) 1992-07-07 US disclosed
EP-0481950-A2 1,4-Dideoxy-4-fluoronojirimycin MONSANTO COMPANY (US) 1992-04-22 EP disclosed
US-5026713-A 1,3-dideoxy-3-fluoronojirimycin which inhibits glycosidase activity MONSANTO COMPANY (US) 1991-06-25 US disclosed
EP-0410953-A2 Piperidine compounds with glycosidase inhibition activity MONSANTO COMPANY (US) 1991-01-30 EP disclosed