Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20639131 | 0.90 | NOTUM (0.53) | NOTUMCYP3A4ACHECFTRCA12 | |
| SCHEMBL25747053 | 0.85 | NOTUM (0.49) | NOTUMCYP3A4ACHECFTRHPGD | |
| SCHEMBL425494 | 0.82 | NOTUM (0.46) | NOTUMCYP3A4ACHECFTRCA12 | |
| SCHEMBL26121538 | 0.82 | NOTUM (0.54) | NOTUMCFTRKDM4ELMNAGABRP | |
| SCHEMBL24076891 | 0.82 | NOTUM (0.46) | NOTUMCFTRKDM4EGABRPGABRD | |
| SCHEMBL10174890 | 0.81 | NOTUM (0.49) | NOTUMCFTRKDM4EGABRPGABRD | |
| SCHEMBL28452116 | 0.79 | CYP3A4 (0.50) | CYP3A4ACHECA12CA1CA2 | |
| SCHEMBL4863532 | 0.78 | CFTR (0.55) | NOTUMCFTRCA12CA1CA2 | |
| SCHEMBL24077140 | 0.77 | NOTUM (0.42) | NOTUMCFTRKDM4ELMNAGABRP | |
| SCHEMBL25355994 | 0.77 | CFTR (0.50) | NOTUMCFTRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066283-A1 | METHIONINE ADENOSYLTRANSFERASE 2A (MAT2A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-04-27 | — | — | WO | disclosed |