Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341597 | 0.94 | MAPK14 (0.41) | MAPK14MAPK13NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1341599 | 0.91 | MAPK14 (0.40) | MAPK14MAPK13NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1342802 | 0.87 | SMN1; SMN2 (0.42) | MAPK14MAPK13NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2648841 | 0.87 | MAPK14 (0.34) | MAPK14MAPK13 | |
| SCHEMBL1343232 | 0.81 | CNR1 (0.42) | MAPK14MAPK13NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1343218 | 0.80 | MAPK14 (0.40) | MAPK14MAPK13NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1342980 | 0.80 | MAPK14 (0.39) | MAPK14MAPK13NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4470766 | 0.79 | SMN1; SMN2 (0.40) | MAPK14MAPK13NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1342702 | 0.79 | MAPK14 (0.40) | MAPK14MAPK13NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6696998 | 0.79 | MAPK14 (0.40) | MAPK14MAPK13NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |