⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL136678 | 1.00 | — | — | |
| SCHEMBL15546709 | 1.00 | — | — | |
| SCHEMBL27873361 | 0.86 | GABRR1 (0.42) | — | |
| SCHEMBL29359095 | 0.74 | — | — | |
| SCHEMBL4284261 | 0.71 | — | — | |
| SCHEMBL4284263 | 0.71 | — | — | |
| SCHEMBL4284258 | 0.71 | — | — | |
| SCHEMBL952357 | 0.71 | — | — | |
| SCHEMBL8353513 | 0.71 | — | — | |
| SCHEMBL13829088 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240262842-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT | MERCK SHARP & DOHME LLC | 2024-08-08 | — | — | US | disclosed |
| EP-4329749-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT | Merck Sharp & Dohme LLC (US) | 2024-03-06 | — | — | EP | disclosed |
| CN-111635312-B | Synthesis method of (E) -2-fluoroalkyl-3-butenoate compound | 安阳师范学院 | 2023-02-21 | — | — | CN | disclosed |
| WO-2022232318-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT | MERCK SHARP & DOHME CORP. (US) | 2022-11-03 | — | — | WO | disclosed |
| CN-113105475-B | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2022-09-09 | — | — | CN | disclosed |
| EP-4003952-A1 | DIFLUOROHALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES, METHODS OF PREPARATION, AND USES THEREOF | Pharmaxis Ltd. (AU) | 2022-06-01 | — | — | EP | disclosed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| CN-113164571-A | Inhibition of ubiquitin-specific peptidase 9X | 福马治疗股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20210002251-A1 | Bruton's Tyrosine Kinase Inhibitors | PFIZER INC. (US) | 2021-01-07 | — | — | US | disclosed |
| US-10815213-B2 | Bruton's tyrosine kinase inhibitors | PFIZER INC. (US) | 2020-10-27 | — | — | US | disclosed |
| US-7094509-B2 | Fluoropolymer containing photoconductive member | XEROX CORPORATION (US) | 2006-08-22 | — | — | US | disclosed |
| US-20050014080-A1 | Photoconductive members | XEROX CORPORATION | 2005-01-20 | — | — | US | disclosed |
| WO-1997002238-A1 | FLUOROBUTENOIC ACID HYDRAZONES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-23 | — | — | WO | disclosed |
| EP-0524041-B1 | Pesticides | ROUSSEL UCLAF (FR) | 1995-09-20 | — | — | EP | disclosed |
| EP-0524041-A2 | Pesticides | ROUSSEL UCLAF (FR) | 1993-01-20 | — | — | EP | disclosed |
| WO-1991003938-A1 | ANTIMICROBIAL POLYMERIC COATING | ECOLAB INCORPORATED (US) | 1991-04-04 | — | — | WO | disclosed |
| EP-0202500-B1 | NOVEL CARBOXYLIC ACID ESTERS, METHODS FOR PRODUCTION THEREOF AND INSECTICIDES CONTAINING THEM AS THE ACTIVE INGREDIENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-02-22 | — | — | EP | disclosed |
| US-4774369-A | ALCOHOLS AS INTERMEDIATES FOR INSECTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-09-27 | — | — | US | disclosed |
| US-4714712-A | Carboxylic acid esters and insecticides containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-12-22 | — | — | US | disclosed |
| EP-0202500-A1 | Novel carboxylic acid esters, methods for production thereof and insecticides containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-11-26 | — | — | EP | disclosed |