SCHEMBL26491771

SCHEMBL26491771

CNC(=O)C(CCC=O)N1Cc2cc(-c3cc(CN4CCCC4)c4ccccc4n3)ccc2C1=O

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MOK Q9UQ07 13/20 0.50
▸ ACP1 P24666 3/20 0.37
▸ DHODH Q02127 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26491751 0.88 MOK (0.36) MOK
SCHEMBL26492047 0.88 MOK (0.36) MOK
SCHEMBL26491818 0.87 MOK (0.35) MOK
SCHEMBL26492494 0.87 MOK (0.35) MOK
SCHEMBL26492121 0.87 MOK (0.35) MOK
SCHEMBL26491774 0.86 ACP1 (0.35) MOKACP1
SCHEMBL26492010 0.85 MOK (0.34) MOK
SCHEMBL26492798 0.85 MOK (0.33) MOK
SCHEMBL26492566 0.84 MOK (0.34) MOK
SCHEMBL26492580 0.84 MOK (0.34) MOK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023183919-A1 BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS ONCOPIA THERAPEUTICS, INC. D/B/A PROTEOVANT THERAPEUTICS, INC. (US) 2023-09-28 — — WO disclosed
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