Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342686 | 0.95 | POLB (0.41) | POLBTP53MAPTPRNPMAPK13 | |
| SCHEMBL1343306 | 0.94 | MAPT (0.40) | POLBTP53MAPTPRNPMAPK13 | |
| SCHEMBL1343246 | 0.87 | MAPT (0.39) | POLBTP53MAPTPRNPMAPK13 | |
| SCHEMBL1342885 | 0.83 | POLB (0.41) | POLBTP53MAPTPRNPMAPK13 | |
| SCHEMBL1343196 | 0.81 | MAPT (0.41) | POLBTP53MAPTPRNPMAPK13 | |
| SCHEMBL4471012 | 0.80 | POLB (0.42) | POLBTP53MAPTMAPK13MAPK14 | |
| SCHEMBL1342605 | 0.80 | POLB (0.41) | POLBTP53MAPTPRNPMAPK13 | |
| SCHEMBL1343240 | 0.80 | MAPT (0.40) | POLBTP53MAPTPRNPGAA | |
| SCHEMBL1340316 | 0.79 | MAPT (0.40) | POLBTP53MAPTPRNPMAPK14 | |
| SCHEMBL1342092 | 0.79 | POLB (0.39) | POLBTP53MAPTPRNPMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |