Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31418420 | 0.88 | TYK2 (0.55) | TYK2PDE4D | |
| SCHEMBL26101273 | 0.88 | TYK2 (0.55) | TYK2PDE4D | |
| SCHEMBL30392474 | 0.86 | TYK2 (0.58) | TYK2PDE4D | |
| SCHEMBL21571880 | 0.86 | TYK2 (0.73) | TYK2PDE4D | |
| SCHEMBL26101587 | 0.84 | TYK2 (0.60) | TYK2PDE4D | |
| SCHEMBL24263461 | 0.81 | TYK2 (0.67) | TYK2PDE4D | |
| SCHEMBL26100998 | 0.80 | TYK2 (0.58) | TYK2PDE4D | |
| SCHEMBL26100797 | 0.80 | TYK2 (0.68) | TYK2PDE4D | |
| SCHEMBL26495339 | 0.80 | TYK2 (0.64) | TYK2PDE4D | |
| Hydrochloric Acid SCHEMBL30392708 | 0.80 | TYK2 (0.58) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |