Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | NCS1 | P62166 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 3/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649551 | 0.93 | TP53 (0.39) | TP53GAANTRK1NTRK2AURKA | |
| SCHEMBL1340595 | 0.91 | TP53 (0.41) | TP53GAANTRK1NTRK2AURKA | |
| SCHEMBL1340546 | 0.88 | TP53 (0.44) | TP53GAANTRK1NTRK2AURKA | |
| SCHEMBL1342895 | 0.81 | NTRK1 (0.55) | TP53GAANTRK1NTRK2AURKA | |
| SCHEMBL1343556 | 0.79 | NTRK1 (0.43) | TP53GAANTRK1NTRK2AURKA | |
| SCHEMBL1342642 | 0.78 | TP53 (0.42) | TP53GAAAURKANCS1SCD | |
| SCHEMBL1342954 | 0.78 | TP53 (0.44) | TP53GAANTRK1NTRK2AURKA | |
| SCHEMBL1343042 | 0.78 | TP53 (0.44) | TP53GAANTRK1NTRK2AURKA | |
| SCHEMBL1342625 | 0.78 | TP53 (0.44) | TP53GAANTRK1NTRK2AURKA | |
| SCHEMBL1341691 | 0.76 | TP53 (0.44) | TP53GAAAURKAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |