Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649897 | 0.89 | PLK1 (0.36) | MAPK14PLK1MAPK13 | |
| SCHEMBL1342443 | 0.82 | POLB (0.39) | MAPK14 | |
| SCHEMBL1343783 | 0.80 | PLK1 (0.41) | MAPK14PLK1MAPK13 | |
| SCHEMBL2650977 | 0.74 | MAPK14 (0.36) | MAPK14MAPK13 | |
| SCHEMBL1344050 | 0.73 | NPSR1 (0.43) | — | |
| SCHEMBL1343546 | 0.72 | MAPK14 (0.39) | MAPK14MAPK13 | |
| SCHEMBL2651299 | 0.70 | POLB (0.40) | MAPK14PLK1MAPK13 | |
| SCHEMBL1342898 | 0.70 | MAPK14 (0.38) | MAPK14MAPK13 | |
| SCHEMBL1343567 | 0.69 | POLB (0.38) | — | |
| SCHEMBL1340704 | 0.69 | POLB (0.41) | MAPK14PLK1MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |