Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26501238 | 1.00 | HRH3 (0.35) | HRH3CYP2D6CYP2C19KCNH2CACNA1I | |
| SCHEMBL26504808 | 0.84 | BCHE (0.36) | HRH3CYP2D6CYP2C19KCNH2CACNA1I | |
| SCHEMBL26501240 | 0.84 | HRH3 (0.40) | HRH3KCNH2KMT2AMEN1LMNA | |
| SCHEMBL26501239 | 0.83 | KMT2A (0.38) | HRH3KMT2AMEN1BCHE | |
| SCHEMBL26749008 | 0.78 | HRH3 (0.39) | HRH3CYP2D6CYP2C19KMT2AKDM4E | |
| SCHEMBL26501220 | 0.78 | PAOX (0.40) | HRH3KCNH2KMT2AMEN1MAPT | |
| SCHEMBL26501223 | 0.78 | PAOX (0.40) | HRH3KCNH2KMT2AMEN1MAPT | |
| SCHEMBL26501219 | 0.78 | PAOX (0.40) | HRH3KCNH2KMT2AMEN1MAPT | |
| SCHEMBL26501233 | 0.78 | PAOX (0.40) | HRH3KCNH2KMT2AMEN1MAPT | |
| SCHEMBL26501216 | 0.78 | PAOX (0.40) | HRH3KCNH2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321253-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321253-A1 | BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF | KRAS, MDM2, NRAS | HRH3 3236/4885CYP2D6 3961/4885CYP2C19 4584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.