Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 20/20 | 0.49 |
| ▸ | GIPR | P48546 | 12/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753876 | 0.93 | GCGR (0.55) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL6750336 | 0.89 | GCGR (0.50) | GCGRGIPRGLP1R | |
| SCHEMBL2650979 | 0.88 | GCGR (0.54) | GCGRGIPR | |
| SCHEMBL2650172 | 0.87 | GCGR (0.58) | GCGRGIPRCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL6752776 | 0.84 | GCGR (0.52) | GCGRGIPRGLP1R | |
| SCHEMBL6752813 | 0.84 | GCGR (0.50) | GCGRGIPRGLP1R | |
| SCHEMBL2651706 | 0.83 | GCGR (0.41) | GCGRGIPRGLP1R | |
| SCHEMBL2664968 | 0.82 | GCGR (0.56) | GCGRGIPR | |
| SCHEMBL6754061 | 0.82 | GCGR (0.52) | GCGRGIPRGLP1R | |
| SCHEMBL6748222 | 0.82 | GCGR (0.45) | GCGRGIPRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040444-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | claimed |