SCHEMBL26501997

SCHEMBL26501997

Bc1cc(O)c(-c2c3ccccc3c(-c3cccc4oc5c6ccccc6ccc5c34)c3ccccc23)c(O)c1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 4/20 0.39
CYP3A4 P08684 3/20 0.38
CYP2C19 P33261 3/20 0.38
TSHR P16473 2/20 0.38
CYP1A1 P04798 8/20 0.36
CYP1A2 P05177 8/20 0.36
CYP1B1 Q16678 8/20 0.36
ABCC1 P33527 2/20 0.36
CYP19A1 P11511 2/20 0.36
TP53 P04637 2/20 0.36
CYP2D6 P10635 2/20 0.36
MAPT P10636 2/20 0.36
CYP2C9 P11712 2/20 0.36
PRKDC P78527 2/20 0.36
KDM4E B2RXH2 1/20 0.36
PDE5A O76074 1/20 0.36
ALDH1A1 P00352 1/20 0.36
ABCB1 P08183 1/20 0.36
HPGD P15428 1/20 0.36
CYP2B6 P20813 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26511115 0.92 ABCG2 (0.42) ABCG2CYP3A4CYP2C19TSHRCYP1A1
SCHEMBL23943263 0.82 CYP3A4 (0.38) ABCG2CYP3A4CYP2C19TSHRCYP1A1
SCHEMBL31747797 0.82 CYP1A1 (0.43) ABCG2CYP3A4CYP2C19TSHRCYP1A1
SCHEMBL18266967 0.82 CYP1A1 (0.43) ABCG2CYP3A4CYP2C19TSHRCYP1A1
SCHEMBL24481911 0.81 CYP1A1 (0.41) ABCG2CYP3A4CYP2C19TSHRCYP1A1
SCHEMBL22908032 0.80 CYP1A1 (0.42) ABCG2CYP3A4CYP2C19TSHRCYP1A1
SCHEMBL18842430 0.80 CYP1A1 (0.42) ABCG2CYP3A4CYP2C19TSHRCYP1A1
SCHEMBL27012231 0.80 ABCG2 (0.43) ABCG2CYP3A4CYP2C19TSHRCYP1A1
SCHEMBL22546760 0.79 CYP1A1 (0.41) ABCG2CYP3A4CYP2C19TSHRCYP1A1
SCHEMBL22541937 0.79 CYP1A1 (0.43) ABCG2CYP3A4CYP2C19TSHRCYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257657-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE Idemitsu Kosan Co.,Ltd. (JP) 2023-10-11 EP disclosed