Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 18/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.53 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31218669 | 1.00 | DDB1 (0.53) | DDB1CRBNDPP4IKZF3 | |
| Hydrochloric Acid SCHEMBL30392488 | 0.99 | DDB1 (0.53) | DDB1CRBNDPP4IKZF3 | |
| SCHEMBL26100189 | 0.94 | DDB1 (0.55) | DDB1CRBNIKZF3 | |
| Hydrochloric Acid SCHEMBL30392788 | 0.94 | DDB1 (0.54) | DDB1CRBNIKZF3 | |
| SCHEMBL25122991 | 0.91 | DDB1 (0.58) | DDB1CRBNIKZF3 | |
| SCHEMBL22835213 | 0.89 | DDB1 (0.57) | DDB1CRBNIKZF3 | |
| Hydrochloric Acid SCHEMBL30393221 | 0.88 | DDB1 (0.56) | DDB1CRBNIKZF3 | |
| SCHEMBL25340445 | 0.84 | DDB1 (0.52) | DDB1CRBNIKZF3 | |
| SCHEMBL25961684 | 0.84 | DDB1 (0.58) | DDB1CRBNIKZF3 | |
| SCHEMBL23728454 | 0.83 | CRBN (0.57) | DDB1CRBNIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |