Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | MAX | P61244 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1340324 | 0.95 | SLC2A1 (0.37) | SLC2A1SMN1; SMN2MAPTHSD17B10NPC1 | |
| SCHEMBL1341862 | 0.95 | SLC2A1 (0.37) | SLC2A1SMN1; SMN2MAPTHSD17B10IRAK4 | |
| SCHEMBL2650841 | 0.92 | SMN1; SMN2 (0.32) | SLC2A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL1340874 | 0.87 | KDM4E (0.38) | SLC2A1SMN1; SMN2MAPTHSD17B10NPC1 | |
| SCHEMBL1341724 | 0.87 | KDM4E (0.38) | SLC2A1SMN1; SMN2MAPTHSD17B10NPC1 | |
| SCHEMBL1343475 | 0.85 | GCK (0.42) | MYCMAXGCK | |
| SCHEMBL1342441 | 0.85 | MKNK2 (0.36) | MYCMAXGCK | |
| SCHEMBL1343582 | 0.84 | SLC2A1 (0.37) | SLC2A1SMN1; SMN2MAPTHSD17B10NPC1 | |
| SCHEMBL1343079 | 0.84 | MYC (0.37) | SLC2A1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL1340361 | 0.84 | MYC (0.37) | SMN1; SMN2MAPTKMT2AMEN1MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |