Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8229172 | 1.00 | CA14 (0.36) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL12184114 | 1.00 | CA14 (0.36) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL13164214 | 0.86 | CA14 (0.38) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL20326295 | 0.85 | CA12 (0.39) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL7997176 | 0.81 | MEN1 (0.35) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL30633537 | 0.81 | MEN1 (0.49) | CA14CA12CA1CA7CA2 | |
| SCHEMBL23645051 | 0.81 | CA14 (0.39) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL2608081 | 0.80 | CA14 (0.49) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL24330036 | 0.80 | CA14 (0.41) | CA14CA12CA1CA7HDAC1 | |
| SCHEMBL25033113 | 0.79 | CA14 (0.36) | CA14CA12CA1CA7HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192873-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-05 | — | — | WO | disclosed |