Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 14/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650483 | 0.93 | FGFR1 (0.48) | FGFR1HPGDTP53MAPTKMT2A | |
| SCHEMBL2648756 | 0.93 | KMT2A (0.46) | FGFR1HPGDTP53MAPTKMT2A | |
| SCHEMBL2649710 | 0.89 | HPGD (0.47) | FGFR1HPGDTP53MAPTKMT2A | |
| SCHEMBL2647728 | 0.88 | FGFR1 (0.52) | FGFR1HPGDKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2648584 | 0.87 | KMT2A (0.47) | FGFR1HPGDTP53MAPTKMT2A | |
| SCHEMBL2653222 | 0.84 | FGFR1 (0.48) | FGFR1HPGDTP53MAPTKMT2A | |
| SCHEMBL2649464 | 0.83 | HPGD (0.47) | FGFR1HPGDTP53MAPTKMT2A | |
| SCHEMBL2649104 | 0.82 | FGFR1 (0.51) | FGFR1HPGDTP53MAPTKMT2A | |
| SCHEMBL2651449 | 0.82 | HPGD (0.50) | FGFR1HPGDTP53MAPTKMT2A | |
| SCHEMBL2648174 | 0.81 | HPGD (0.46) | FGFR1HPGDKMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002050057-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES FOR THE TREATMENT OF GABA-ALPHA MEDIATED DISORDERS | NEUROSEARCH A/S (DK) | 2002-06-27 | — | — | WO | claimed |
| WO-2002050057-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES FOR THE TREATMENT OF GABA-ALPHA MEDIATED DISORDERS | NEUROSEARCH A/S (DK) | 2002-06-27 | — | — | WO | disclosed |